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Blood Biochemical, Enzymatic and Haematological Status of Dogs Affected with Dilated Cardiomyopathy


 
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1. Title Title of document Blood Biochemical, Enzymatic and Haematological Status of Dogs Affected with Dilated Cardiomyopathy
 
2. Creator Author's name, affiliation, country P. S. L. Sesh; Department of Veterinary Physiology and Biochemistry, Veterinary College and Research Institute, Tirunelveli, Tamil Nadu; India
 
2. Creator Author's name, affiliation, country P. Venkatesan; Department of Veterinary Biochemistry, Madras Veterinary College, Chennai, Tamil Nadu; India
 
2. Creator Author's name, affiliation, country K. Jeyaraja; Department of Clinics, Madras Veterinary College, Chennai, Tamil Nadu; India
 
2. Creator Author's name, affiliation, country M. Chandrasekar; Department of Veterinary Clinical Medicine Ethics and Jurisprudence, Madras Veterinary College, Chennai,Tamil Nadu; India
 
2. Creator Author's name, affiliation, country V. Pandiyan; Department of Veterinary Biochemistry, Madras Veterinary College, Chennai, Tamil Nadu; India
 
3. Subject Discipline(s) Cliical veterinary Biochemistry
 
3. Subject Keyword(s) DCM, Dogs, Cardiology, Biochemical Parameters, Cardiac Enzyme Markers, Haematological Parameters
 
3. Subject Subject classification Canine cardiology
 
4. Description Abstract

Dilated Cardiomyopathy (DCM) occurs more frequently in large breed dogs and the common form is Idiopathic DCM. Blood biochemical and enzymatic parameters pertaining to cardiology were analysed in both healthy and DCM affected dogs. The activity of creatine kinase increased significantly while the concentration of sodium and calcium decreased significantly in DCM cases. Significant differences in the concentration of potassium, creatinine, urea and total cholesterol were observed, but the values were well within the normal range. The concentration of other blood biochemical parameters like glucose, total proteins, HDL-cholesterol, LDL-cholesterol, triglycerides and the activity of the enzymes AST and LDH were all within the normal range and showed no significant variation between the healthy and DCM dogs. Similarly, haematological parameters were also analysed in both healthy and DCM affected dogs. There was a significant decrease in the concentration of Haemoglobin, PCV (%), RBC count and Platelet count in DCM affected dogs. However, the total WBC counts were significantly higher; with DLC showing neutrophilia in DCM affected dogs. Thus the overall picture indicated Ischemia with acute infection.

 
5. Publisher Organizing agency, location
 
6. Contributor Sponsor(s)
 
7. Date (YYYY-MM-DD) 2013-04-23
 
8. Type Status & genre Peer-reviewed Article
 
8. Type Type
 
9. Format File format PDF
 
10. Identifier Uniform Resource Identifier http://scientific.cloud-journals.com/index.php/IJAVST/article/view/Sci-90
11. Source Journal/conference title; vol., no. (year) International Journal of Advanced Veterinary Science and Technology; Volume 2 (Year 2013)
 
12. Language English=en en
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.) India
 
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