The study was conducted from April 2009 to March 2010 to assess the antimicrobial sensitivity pattern of eight Salmonella Gallinarum strains recovered from various sources in Jaipur of India by testing with eight different antimicrobials by disc diffusion method where the isolates showed least sensitive to tetracycline. Gross lesions incriminated to the pathogen, were comprised of caseous enteritis, hepatic necrosis, necrotizing myocarditis and oophoritis. Histopathological investigation revealed passive congestion of the visceral organs. Degenerative changes in hepatic lobules and consequential destruction of architectural arrangement of hepatocytes, necrotic foci in the enteric mucosa and in hepatic tissues were seen. Ovaries showed fibrinosuppurative to pyogranulomatous inflammation of ovarian follicles characterised by necrosis and fibrinosuppurative inflammation mixed with bacteria within the ovules to chronic pyogranulomatous inflammation. Heart characterised by locally extensive foci of myofibre necrosis with infiltration of heterophils mixed with few lymphocytes and plasma cells.